At least 46 people were killed and several others suffered injuries as fire engulfed an express train in Liaqatpur near Rahim Yar Khan on Thursday morning, Pakistani media reported.
The incident took place in the wee hours when the three coaches of in Karachi-Rawalpindi Tezgam express train caught fire. The train was en route for Lahore from Karachi.
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The injured are being shifted to nearby hospitals. Rescue operations are underway.
Further details are awaited.