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International COVID-19 Variants You Should Know & Why Are They Concerning

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With over 3 lakh cases being reported every day, India is reeling under a terrible second wave of Covid-19. Just a month back, India had reported just 44,000 odd cases per day. The sudden surge has taken everyone by surprise. Health care infrastructure has been overwhelmed with patients and urgent need for oxygen and supplies. In the midst of the pandemic, SARS-CoV-2 has already undergone several thousand mutations in India and internationally as well. Some variants are more concerning than others. Here are the international variants which have come under the scanner of the international community.

INDIAN VARIANT
B.1.617 has been categorised by the World Health Organization as a “variant of interest”. B.1.617 is one of the known variants of SARS-CoV-2, the virus that causes COVID-19. This variant was first identified in India on 5 October 2020 and is a “double mutation” variant.
INDIAN VARIANT-BENGAL STRAIN
Another ‘triple mutant variant’ or the ‘Bengal strain’ B.1.618 is a new variant of the Covid-19 virus that has been detected in India. Experts say this variant is more infectious and is spreading rapidly. The new variant, B.1.618, has a major mutation called E484K. This mutation helps it evade the immune system and also compromise vaccine efficacy.

UK OR KENT VARIANT

The UK variant B.1.1.7 is dominant in Britain and has spread to more than 50 countries. This strain emerged in the UK with many mutations. This variant has since been detected in numerous countries around the world, including the United States (US). In January 2021, scientists from UK reported evidence that suggests the B.1.1.7 variant may be associated with an increased risk of death compared with other variants.

SOUTH AFRICA VARIANT

The South Africa variant B.1.351 has found in at least 20 other countries. This variant of SARS-CoV-2 emerged independently of B.1.1.7.  The South African variant carries a mutation, N501Y that appears to make it more contagious or easy to spread.
BRAZIL VARIANT

In Brazil, a variant of SARS-CoV-2 which is known as P.1 emerged and was first identified in four travellers from Brazil. This variant has 17 unique mutations. A new study suggests the variant known as P.1 is able to reinfect people who had already tested positive.

Why does the Coronavirus Mutate?

All viruses naturally mutate over time, and Sars-CoV-2 is no exception. Variants of viruses occur when there is a change in the virus’ gene.

Why We Need To Keep An Eye On Mutating Viruses

SARS-CoV-2 strain surveillance helps to build a collection of SARS-CoV-2 specimens and sequences to support public health response. Analysis of the available genetic sequence data can help countries fight COVID-19. Here is why the mutants are dangerous:

  • Can spread more quickly in people.
  • Can cause either milder or more severe disease in people.
  • Ability to evade detection by specific viral diagnostic tests
  • Decreased susceptibility to therapeutic agents such as monoclonal antibodies
  • Can evade natural or vaccine-induced immunity

 

(Source: CDC)

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